United States Precision Medicine Market Analysis Report 2025-2033: Developments in Biomarker Identification and Genomic Sequencing, & Combining Big Data Analytics and AI Fuel Growth

The Precision Medicine Market in the U.S. is projected to grow from $26.58 billion in 2024 to $62.82 billion by 2033, with a CAGR of 10.03%. Key drivers include advancements in genomics, AI applications, government support, and rising investments in R&D. Regional partnerships and genomic sequencing innovations play a pivotal role too. Major states like California, Texas, New York, and Florida are leading the charge, supported by strong healthcare infrastructure and research initiatives. However, challenges such as high costs and data privacy concerns persist. Key players like AstraZeneca plc and Illumina Inc . are integral to this growth.

Dublin, Oct. 24, 2025 (GLOBE NEWSWIRE) -- The "United States Precision Medicine Market Report by Product, Technology, Application, End User, States and Company Analysis, 2025-2033" report has been added to ResearchAndMarkets.com's offering.

United States Precision Medicine Market is expected to reach US$ 62.82 billion by 2033 from US$ 26.58 billion in 2024, with a CAGR of 10.03% from 2025 to 2033

Government support for personal medicine, the rise in chronic diseases, the adoption of AI and machine learning technologies, the development of genomics technology, the expansion of healthcare data, and regional partnerships between tech companies and healthcare institutions are the main factors propelling the market.

The U.S. precision medicine market demonstrates strong regional growth, with California, Texas, New York, and Florida emerging as key hubs due to advanced research institutions, healthcare infrastructure, government initiatives, and expanding industry collaborations.



The high incidence of chronic illnesses in the US is the main factor propelling the market. such as cardiovascular diseases and cancer. For example, the U.S. Food & Drug Administration found that common chronic diseases (CCDs) account for seven of the top 10 causes of mortality in the United States, with diet-related conditions like obesity, diabetes, cardiovascular disease, and several types of cancer playing a major role. The demand for a special therapeutic intervention is being fueled by the fact that 28 million Americans still smoke and yet the United States has diet-related disease rates that are lower than those of 42 other countries. The market is expanding as a result of ongoing technological advancements in genetics and bioinformatics that enhance the design of personalized medicines.

In addition, rising investments by pharmaceutical companies into precision medicine research and development operations are adding momentum to the precision medicine market in the United States. The solutions are also becoming more widely available thanks to government initiatives that foster creative healthcare solutions and finance precision medicine initiatives, which encourage wider market adoption across healthcare systems. Additionally, more precise patient profiling and treatment customization are being encouraged by the growing integration of AI and big data analytics in healthcare, which is fueling market expansion.

An important element driving market expansion is the growing availability of direct-to-consumer genetic testing services, which are raising patient awareness and involvement. In addition, research centers and healthcare service providers are forming strategic collaborations that accelerate the conversion of research findings into clinical practice, so promoting growth. To enhance pandemic readiness, for example, Care Access announced on August 26, 2024, a multimillion-dollar partnership with the Biomedical Advanced Research and Development Authority (BARDA) of the U.S. Department of Health and Human Services.

Through the cooperation, Care Access's decentralized clinical trial network will expand to include up to 150 community-based clinicians from 30 regions, community groups in underserved areas, and long-term care providers nationally. The program guarantees equitable healthcare for all varied communities and attempts to increase access to immunizations and treatments during public health emergencies. The demand for precision medicine solutions is rising as a result of growing interest in reducing adverse drug responses and enhancing treatment efficacy, which further supports the market forecast in the US.

Key Factors Driving the United States Precision Medicine Market Growth

Developments in Biomarker Identification and Genomic Sequencing

Because it allows physicians to decipher patient-specific genetic profiles and create highly customized treatment plans, genomic sequencing has emerged as the foundation of precision medicine. Next-generation sequencing (NGS) technologies have advanced quickly, improving the speed, accuracy, and cost-effectiveness of genomic analysis while boosting accessibility across healthcare systems. By finding genetic mutations, protein expressions, or metabolic markers that inform treatment choices, biomarker discovery further improves diagnostic precision.

Biomarkers are essential in oncology because they help determine medication response and tumor behavior, which enhances treatment results and minimizes side effects. Additionally, by enabling medication developers to target certain patient populations instead of depending on broad-spectrum medicines, these improvements speed up pharmaceutical R&D. Genomic sequencing and biomarker discovery will continue to be a key growth driver as costs continue to drop and technology advance, encouraging the broad use of individualized care across the US.

Combining Big Data Analytics and Artificial Intelligence

By facilitating the real-time processing of complicated patient data, the emergence of artificial intelligence (AI) and big data analytics is substantially propelling the precision medicine market in the United States. Massive datasets, such as genetic profiles, medical imaging, and electronic health records, can be analyzed by AI-powered algorithms to produce insights that physicians can use. Predictive models aid in early illness risk assessment, treatment plan customization, and efficient resource distribution within healthcare systems.

AI also speeds up drug research by more accurately identifying possible treatment candidates and simulating molecular interactions. By identifying illness trends and treatment efficacy on a broader scale, big data analytics improves population health management. When combined, these tools reduce trial-and-error methods and promote more precise clinical decision-making. One of the key elements propelling expansion in the precision medicine market in the United States is the combination of AI and data-driven technologies, which not only enhances patient outcomes but also lowers healthcare expenses.

Increasing Government Assistance and Funding for Research

The advancement of precision medicine in the US is greatly aided by government funding and initiative programs. The nation's dedication to creating individualized care solutions was demonstrated by the federal government's establishment of the Precision Medicine Initiative (PMI). Large-scale research initiatives like the "All of Us" initiative, which attempts to gather genetic, lifestyle, and environmental data from varied populations, have received significant funding from federal institutions like the National Institutes of Health (NIH).

These programs are encouraging creativity, advancing public-private partnerships, and guaranteeing that the advantages of precision medicine are distributed throughout communities. Additionally, biotechnology and pharmaceutical companies are being encouraged to hasten the development of targeted medicines and diagnostics by supportive policies and favorable regulatory processes. Government funding keeps the precision medicine ecosystem strong by emphasizing innovation, data infrastructure, and inclusivity, guaranteeing that the US stays at the forefront of this changing healthcare paradigm.

Challenges in the United States Precision Medicine Market

High Costs and Limited Accessibility

The high expense of advanced diagnostics, individualized treatments, and genomic testing is one of the main obstacles facing the U.S. precision medicine sector and may prevent some patients from accessing these treatments. Even though sequencing costs have decreased dramatically in recent years, underinsured people and those living in rural or underserved areas frequently cannot afford thorough tests and individualized therapies.

Inconsistent insurance coverage for precision medical services leads to differences in adoption among various socioeconomic groups. Large-scale adoption is hampered by this pricing gap since precision medicine runs the risk of becoming exclusive to affluent groups. Achieving equal access is still difficult in the absence of efficient cost-cutting measures and expanded insurance coverage, which could impede the rate of broad integration into mainstream healthcare systems across the US.

Issues with Data Security, Privacy, and Interoperability

The gathering and examination of private patient data, such as genetic information, lifestyle choices, and medical records, is essential to precision medicine. Critical questions concerning data security, privacy, and interoperability across healthcare systems are brought up by this dependence. Given the increasing frequency of cyberattacks on healthcare infrastructure, safeguarding patient data against breaches and illegal usage is a major concern.

Furthermore, the absence of uniform data-sharing guidelines among medical facilities, academic institutions, and technology suppliers leads to inefficiencies and impedes cooperation. Concerns over the storage and use of their genetic data may potentially make patients reluctant to engage in precision medicine initiatives. Gaining patient trust and facilitating widespread adoption require ensuring secure data management, creating interoperable systems, and upholding transparency. Despite technological developments, the market's potential for growth may be limited if these issues are not resolved.

Key Attributes:

Recent Developments in U.S. Precision Medicine Market

• A significant breakthrough in precision medicine was made on October 31, 2024, when Ataraxis AI introduced Ataraxis Breast, the first AI-native prognostic and predictive test for breast cancer. In a groundbreaking study, the test was clinically validated and showed a 30% increase in accuracy compared to the current standard of care. To further its development, the company also obtained USD 4 million in seed funding, which was co-led by Giant Ventures and Obvious Ventures.
• Patient enrollment for myeloMATCH was launched on October 23, 2024 by four leading cancer research organizations: SWOG Cancer Research Network, ECOG-ACRIN Cancer Research Group, Canadian Cancer Trials Group, and the Alliance for Clinical Trials in Oncology. The National Cancer Institute's National Clinical Trials Network oversees this portfolio of precision medicine clinical trials that focus on myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). With biomarker-driven treatment options available throughout their care, the program hopes to enroll more than 5,000 patients in the United States and Canada.

Company Analysis: Overview, Key Persons, Recent Developments, SWOT Analysis, Revenue Analysis

• AstraZeneca plc
• Bayer AG
• bioMerieux SA
• Bristol-Myers Squibb Company
• Eli Lilly and Company
• F. Hoffmann-La Roche AG
• Illumina Inc .
• Laboratory Corporation of America Holdings
• Merck KGaA KGaA
• Novartis AG

Market Segmentations

Product

• Consumables
• Instruments
• Services

Technology

• Big Data Analytics
• Bioinformatics
• Gene Sequencing
• Drug Discovery
• Companion Diagnostics
• Others

Application

• Oncology
• Central Nervous System (CNS)
• Immunology
• Respiratory Medicine
• Infections
• Others

End User

• Hospitals and Clinics
• Diagnostic Centers
• Pharma and Biotech Companies
• Healthcare IT Firms
• Others Export

States

• California
• Texas
• New York
• Florida
• Illinois
• Pennsylvania
• Ohio
• Georgia
• New Jersey
• Washington
• North Carolina
• Massachusetts
• Virginia
• Michigan
• Maryland
• Colorado
• Tennessee
• Indiana
• Arizona
• Minnesota
• Wisconsin
• Missouri
• Connecticut
• South Carolina
• Oregon
• Louisiana
• Alabama
• Kentucky
• Rest of United States

For more information about this report visit https://www.researchandmarkets.com/r/b53a8x

About ResearchAndMarkets.com
ResearchAndMarkets.com is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends.

Attachment

• U.S. Precision Medicine Market

CONTACT: 
CONTACT: ResearchAndMarkets.com 
         Laura Wood, Senior  Press Manager 
         press@researchandmarkets.com
         For E.S.T Office Hours Call 1-917-300-0470 
         For U.S./ CAN Toll Free Call 1-800-526-8630 
         For GMT Office Hours Call +353-1-416-8900